Aerospace and Mechanical Engineering
Describe your undergraduate research or creative project:
Recently, three-dimensional computational models have been used to understand the mechanics of heart valve diseases. To improve the fidelity of these models, precise characterization of the regionally-dependent material properties of the valve leaflets is essential. To characterize this regional variation, we dissected the porcine heart valve tissues and sectioned the anterior leaflets from the mitral and tricuspid valves into six discretized regions (n=10, each). We then characterized their responses to simulated physiological loads through biaxial testing methods. Results show a regionally-dependent mechanical response both in the degree of anisotropy and in tissue rigidity, with regions nearer the valve annulus exhibiting a more isotropic and stiff response than the central regions. These findings allow the development of spatially-varied constitutive models to adequately represent the leaflet mechanics, which will eventually improve the fidelity of heart valve models and their...
Awards and/or presentations:
Jett, Samuel. "A Study on the Spatial Variance in Heart Valve Mechanics." Curiosity to Creativity Spring Symposium, 25 April 2018, Oklahoma Memorial Union, Norman, OK.