Devin Laurence

OU Major: 
Aerospace and Mechanical Engineering
Research Mentor: 
Dr. Chung-Hao Lee
Describe your undergraduate research or creative project: 
The tricuspid valve (TV) helps facilitate the unidirectional blood flow through the heart during regular function. About 50,000 Americans undergo surgical repair annually to correct leaflet regurgitation; however, there is a disappointing recurrence rate (15-20%) of tricuspid regurgitation approaching 10 years after the initial repair1-3. The objective of our research is to better understand the distinct leaflet contributions to TV mechanical behavior through a multi-scale computational model. The computational model is built and refined through an experimental-computational approach with three key ingredients: (i) biaxial experiments to quantify the TV leaflets' mechanical behavior, (ii) development of a post-mortem beating heart apparatus for imaging functioning valves, and (iii) application of the acquired experimental information to validate the computational model. This approach will provide the groundwork for future extensions into patient-specific heart valve modelling...
Awards and/or presentations: 
Laurence, Devin. "Development of a Multiscale Computational Modeling Framework for the Tricuspid Valve." Curiosity to Creativity Spring Symposium, 25 April 2018, Oklahoma Memorial Union, Norman, OK